Reference Values for Large Animals

Temperature, pulse rate, and respiratory rate (TPR) ranges

Cow Horse Pig Sheep Goat
Temperature
Young animal
101.5-103.0ºF
(39-40.5ºC)
99.0-102.0ºF
(37.0-39.0ºC)
102-104ºF
(38.9-40.0ºC)
102.5-104ºF
(39.5-40.5ºC)
102-104ºF
(39-40.5ºC)
Adult animal 100-102.5ºF
(38-39ºC)
99.0-100.6ºF
(37.2-38.1ºC)
101.6-103.6ºF
(38.7-39.8ºC)
102-103.5ºF
(39-40ºC)
101.5-103.5ºF
(38.5-39.5ºC)
Pulse rate
(beats per min)
Young animal
100-140 80-100 ( 40-80 (3mo-1yr) 100-130 120-160 120-160
Adult animal 40-80 28-40 70-120 60-180 70-110
Respiratory rate
(breaths per minute)
Young animal
30-60 30-35 20-40 30-70 40-65
Adult animal 12-36 10-14 32-58 12-72 15-40

Adult serum (plasma) biochemical reference ranges

Parameter Units Cow Horse Pig Sheep Goat
Alanine aminotransferase
(ALT)
IU/L N/A N/A 22-47 26-34 6-19
Amylase IU/L N/A N/A 44-88 N/A N/A
Alkaline phosphatase (ALP) IU/L 0-488 76-262 41-176 68-387 93-387
Anion gap mEq/L 14-20 11-26 N/A N/A N/A
Aspartate aminotransferase (AST) IU/L 78-132 194-431 15-55 60-280 167-513
Bicarbonate mEq/L 17-29 21-31 18-27 20-25 N/A
Bilirubin, total mg/dL 0.01-0.5 0.4-2.8 0.0-0.5 0.1-0.5 0-0.1
Bilirubin, indirect
(unconjugated)
mg/dL 0-0.3 0.1-2.8 N/A 0-0.12 0-0.1
Bilirubin, direct
(conjugated)
mg/dL 0.04-0.44 0.2-0.6 N/A 0-0.27 0-0.1
Calcium (total) mg/dL 9.7-12.4 10.2-12.8 9.3-11.5 11.5-12.8 8.9-11.7
Chloride mEq/L 97-111 96-106 97-106 95-103 99-110
Cholesterol mg/dL 80-120 49-150 81-134 52-76 80-130
Creatine kinase (CK) IU/L 44-211 130-497 66-489 64-158 104-219
Creatinine mg/dL 1.0-2.0 0.8-1.8 0.8-2.3 1.2-1.9 1.0-1.8
Gamma-glutamyl transferase (GGT) IU/L 15-39 9-37 31-52 40-79 20-56
Glucose mg/dL 45-75 49-102 66-116 50-80 50-75
Lactate dehydrogenase (LDH) IU/L 697-1445 102-341 160-425 238-440 123-392
Magnesium mg/dL 1.8-2.3 1.2-1.9 2.3-3.5 2.2-2.8 2.8-3.6
Osmolality mOsm/kg 270-300 270-300 N/A N/A N/A
pCO2 mmHg 35-44 38-46 N/A 37-46 N/A
pH N/A 7.31-7.53 7.32-7.44 N/A 7.32-7.54 N/A
Phosphorus mg/dL 5.6-6.5 2.0-4.8 5.5-9.3 5.0-7.3 6.5
Potassium mEq/L 3.9-5.8 2.5-5.2 2.5-5.2 3.9-5.4 3.5-6.7
Protein (total)
Albumin
Globulin
g/dL
g/dL
g/dL
6.74-7.46
3.0-3.55
3-3.48
5.5-7.5
3.0-3.9
2.3-4.1
5.8-8.3
2.3-4.0
3.9-6.0
6.0-7.9
2.4-3
3.5-5.7
6.4-7
2.7-3.9
2.7-4.1
SDMA µg/dL N/A 11-25 N/A N/A N/A
Sodium mEq/L 132-152 132-141 139-153 139-152 142-155
Sorbitol dehydrogenase (SDH) IU/L 4.3-15.3 4.3-15.3 0.5-4.9 5.8-27.9 14-23.6
TCO22 mEq/L 21-32 21-31 N/A 21-28 26-30
Urea nitrogen (BUN) mg/dL 20-30 11-25 8-24 8-20 10-20
Urinalysis
Urine specific gravity
(USpG)
N/A 1.030-1.045 1.025-1.060 1.010-1.050 1.015-1.045 1.015-1.045
Urine volume
(ml/kg body wt/day)
N/A 17-45 3-18 5-30 10-40 10-40

Adult hematologic reference ranges (complete blood count [CBC] and differential)

Conv. (USA) Units SI Units Cow Horse Pig Sheep Goat
Hematocrit % 102L/L 22-33 32.5-46.5 32-50 27-45 22-38
Hemoglobin
(Hgb)
g/dL 10 g/L 8.5-12.2 11.4-17.3 10-16 10-16 8-18
Erythrocytes x 106/µL 1012g/L 5.1-7.6 6.30-10.90 5-7 9-15 13.6-23.7
Reticulocytes % % 0 0 0-12 0 0
Mean corpuscular volume (MCV) fL fL 38-50 39-55 52-62 28-40 16-25
Mean corpuscular Hgb (MCH) pg pg 11-17 14.6-19.1 17-24 8-12 5.2-8
Mean corpuscular Hgb concentration (MCHC) g/dL 10 g/L 36-39 33.6-38.6 29-34 31-34 30-36
Platelets x 103/µL 1011/L 100-800 70-250 2-5 800-1100 800-1100
White blood cells x 103/µL 109/L 4.9-12 4.3-11.4 11-22 4-12 4-13
Neutrophils (segmented) x 103/µL x 109/L 1.8-6.3 2.46-7.23 2-15 0.7-6.0 1.2-7.2
Neutrophils (band) x 103/µL x 109/L rare 0 0-0.8 rare rare
Lymphocytes x 103/µL x 109/L 1.6-5.6 1.45-5.0 3.8-16.5 2-9 2.6-11.7
Monocytes x 103/µL x 109/L 0-0.8 0-0.6 0-1 0-0.75 0-0.9
Eosinophils x 103/µL x 103/µL 0-0.9 0-0.7 0-1.5 0-1 0-1
Basophils x 103/µL x 109/L 0-0.3 0-0.1 0-0.5 0-0.3 0-0.3
Neutrophil to lymphocyte ratio N/A N/A 0.4-2.34 0.8-2.8 N/A 0.3-0.7 0.6-3.60
Total protein g/dL x 10 g/L 6-8 5.6-7.9 6-8 6-7.5 6-7.75
Plasma fibrinogen mg/dL x 10 g/L 200-700 100-400 0.2-0.4 0.1-0.5 0-200

Note: Normal ranges vary based on patient age. Please review specific laboratory reference ranges for neonates and young animals.
Reference values vary by lab and by reference cited. In practice, refer to the normals listed by the specific laboratory for reference values applicable to your clinical situation.

References:

Duncan and Prasse, Clinical Pathology, 4th ed. (Latimer, Mahaffey and Prasse) pp. 331-38
Merck Veterinary Manual online edition, Reference values section
Cornell’s eclinpath website
Smith, Van Metre, and Pusterla’s Large Animal Internal Medicine, 6th ed